Multispectral Optoacoustic Tomography (MSOT) for the Evaluation of Head and Neck Diseases

Not Applicable

Recruiting

Conditions: C00-C14
C30
C31
C32
D37.0
D38.0
D38.5
C73
Malignant neoplasms of lip, oral cavity and pharynx
Malignant neoplasm of nasal cavity and middle ear

Registration Number: DRKS00023331

Lead Sponsor: niversitätsklinikum Freiburg

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 50

Inclusion Criteria

Basically, patients who can be treated in our clinic on an outpatient or inpatient basis are eligible

In principle, it must be possible to visualize the disease by means of imaging in order to be able to determine the indication for resection independently of the planned study examination.

Before study enrollment, patients are informed in detail about the purpose of the study and the possible risks. They are also informed about basic issues such as data protection, etc. (see patient information).

Sufficient amounts of normal tissue must adhere to the preparation to be examined in order to enable the comparison of tumor tissue and normal tissue

Age: =18 years

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Exclusion Criteria

Disease cannot be visualized with the clinic's own ultrasound

Non-existing or limited legal capacity

Not enough normal tissue in the resected tissue for comparison of tumor tissue and normal tissue

Age < 18 years

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary endpoint is to demonstrate that tumor resection from the head and neck region with adherent normal tissue can be distinguished from surrounding normal tissue using MSOT, with a focus on pathologies in the salivary glands and cervical lymph nodes.

Secondary Outcome Measures

Name	Time	Method
Secondary endpoints are MSOT-specific characteristics of the disease that go beyond the sonographically generated information such as size, shape or echogenicity, such as water or fat content or oxygen saturation of hemoglobin, which can be detected in normal salivary gland tissue and tumor tissue depending on the laser wavelength used.