Multispectral Optoacoustic Tomography (MSOT) as a non-invasive biomarker in diagnostics and follow-up of myopathies
Recruiting
- Conditions
- Hereditary Myopathies idiopathic inflammatory myopathies
- Registration Number
- DRKS00033176
- Lead Sponsor
- niversitätsmedizin Göttingen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 552
Inclusion Criteria
Confirmed diagnosis of a myopathy evaluated in this study
- able to give consent
Exclusion Criteria
- Unclear neuromuscular disorder or symptoms, NMD not evaluated in this study
- unable to give consent
- pregnancy
- tattoos of the skin in the examinated area
- severe peripheral arterial disease
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Optoacoustic absorption spectrum of skeletal muscle in different myopathies
- Secondary Outcome Measures
Name Time Method MSOT: quantitative lipide, collagen, haemo-/myoglobine, glycogene signal, muscle oxygenation<br>RUCT (Hybrid reflected ultrasound computed tomography): Heckmatt scale, echogenity, grey value <br>Clinical parameters: muscle strength, grip strength, 6 minute walking test, time to get up and go test<br>Disease specific patient reported scales <br>Vital capacity