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Analysis of temporal and spatial diversity of RAS gene mutations in metastatic colorectal cancer

Not Applicable
Recruiting
Conditions
Metastatic colorectal cancer
Registration Number
JPRN-UMIN000053017
Lead Sponsor
Kanagawa Cancer Center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
200
Inclusion Criteria

Not provided

Exclusion Criteria

Colitic cancer

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The incidence of NeoRAS wild-type
Secondary Outcome Measures
NameTimeMethod
1. Percentage of RAS status mutations during chemotherapy. 2. Percentage of neo-RAS wild-type anti-EGFR antibodies used. 3. RAS mutation rates in tissue samples and liquid biopsy. 4. Overall survival, progression-free survival of neo RAS wild-type and RAS mutant
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