Study of the Effects of Three Strawberry Jams, Differing in Carbohydrate and Antioxidant Content, on Postprandial Response in Healthy Subjects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 16
- 试验地点
- 2
- 主要终点
- Plasma malondialdehyde (MDA) postprandial measure
研究概览
简要总结
The aim of this study is to investigate the effects of an acute intake of three different types of strawberry jam, differing in the carbohydrates and antioxidants content, on postprandial glucose metabolism, lipid profile, antioxidant status and satiety indices, in healthy adults.
详细描述
Study Design: Randomized, postprandial, crossover, double-blind intervention with three arms.
Subjects: Sixteen healthy adults
Product studied: At each arm, participants consume 60g of strawberry jam:
- High-sugar jam (traditional; HS),
- Low-sugar jam (without added-sugar; LS),
- Low-sugar jam including antioxidant extract from strawberry pulp (LSA).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adult men and women
- •Normal weight or overweight (BMI between 18.5 and 29.9 kg/m2)
- •Age between 20 and 50 years old.
排除标准
- •To suffer from any chronic disease related to metabolism,
- •To follow concomitant medications,
- •To follow slimming treatments or hormone replacement therapy,
- •To have any inability to perform the follow-up,
- •Known food allergies,
- •Pregnancy, lactation or menopause
研究组 & 干预措施
High Sugar (HS)
Study of the postprandial effects after consuming 60g of strawberry jam with high sugar content
干预措施: Strawberry Jam (Other)
Low Sugar (LS)
Study of the postprandial effects after consuming 60g of strawberry jam with low sugar content
干预措施: Strawberry Jam (Other)
Low Sugar + Antioxidant (LSA)
Study of the postprandial effects after consuming 60g of strawberry jam with low sugar content and an antioxidant extract from strawberry pulp
干预措施: Strawberry Jam (Other)
结局指标
主要结局
Plasma malondialdehyde (MDA) postprandial measure
时间窗: up to 120 minutes
Plasma MDA measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam
次要结局
- Serum insulin postprandial concentration(baseline, 30, 60, 90 and 120 minutes)
- Serum Uric Acid postprandial concentration(Baseline, 30, 60, 90 and 120 minutes)
- Serum glucose postprandial concentration(Baseline, 30, 60, 90 and 120 minutes)
- Plasma Glutathione Peroxidase postprandial activity(Baseline, 30, 60, 90 and 120 minutes)
- HOMA insulin resistance index(Baseline, 30, 60, 90 and 120 minutes)
- Serum total cholesterol postprandial concentration(Baseline, 30, 60, 90 and 120 minutes)
- Serum LDL-cholesterol postprandial concentration(Baseline, 30, 60, 90 and 120 minutes)
- Postprandial Plasma Total Antioxidant Capacity(Baseline, 30, 60, 90 and 120 minutes)
- Serum HDL-cholesterol postprandial concentration(Baseline, 30, 60, 90 and 120 minutes)
研究者
Alfredo Martinez
Professor of Nutrition and Food Science
Clinica Universidad de Navarra, Universidad de Navarra