Prospective study of efficacy of Negative-pressure wound therapy (NPWT) for dirty abdominal wound after lower gastrointestinal perforation.

Not Applicable

• Conditions: ower gastrointestinal perforation

• Registration Number: JPRN-UMIN000020391
• Lead Sponsor: Multicenter Clinical Study Group of Osaka, Colorectal Cancer Treatment Group

Brief Summary

Five patients had surgical site infections (SSIs) during NPWT and did not receive a DPC (9%). Of the 51 patients that received DPCs, 44 had no infection (91%) and 7 developed SSIs after the DPC (13.7%). For stages II, III, and IV, the SSI rates were 0%, 22.6%, and 35.7%, respectively; the median (range) times to wound healing were 15 (10-36), 19 (11-99), and 19 (10-53) days, respectively. There were no significant differences between the stages.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-12-30
• Study Completion: 2017-08-16
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 51

Inclusion Criteria

Not provided

Exclusion Criteria

1, Naked blood vessel suspected of bleeding or surgical site infection to directly contact to other organs or the presence of fistula to abdominal cavity. 2, The presence of organ/space surgical site infection 3, The patient corresponding to the VAC treatment system Contraindications. 4, As determined by the principal investigator or the sub-investigator the subject is not adequate to participate in the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified