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临床试验/NCT02124382
NCT02124382已完成不适用

Living Donor Liver Transplantation in Children: Surgical and Immunological Results in 250 Recipients at Université Catholique de Louvain.

Cliniques universitaires Saint-Luc- Université Catholique de Louvain0 个研究点目标入组 500 人开始时间: 2012年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
500
主要终点
Patient and graft survival

研究概览

简要总结

Evaluate the outcome of pediatric living donor liver transplantation (LDLT) regarding portal vein reconstruction, ABO-compatibility and impact of maternal donation on graft acceptance.

详细描述

Data from 250 pediatric LDLT recipients (and their donors), transplanted at Cliniques universitaires Saint-Luc between July 1993 and June 2012, were collected retrospectively using electronic data files. Results were analysed according to ABO matching and portal vein complications. Uni- and multi-variate analysis was used to study the impact of immunosuppression, gender match and maternal donation on acute rejection rate.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
— 至 57 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Children receiving a living donor liver transplant
  • Adult living donors

排除标准

  • 未提供

结局指标

主要结局

Patient and graft survival

时间窗: 10 years

Kaplan-Meier

次要结局

  • Portal vein complications(10 years)

研究者

发起方
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
申办方类型
Other
责任方
Sponsor

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