NCT05049395
Unknown
Not Applicable
HFNO Reducing the Incidence of Hypoxia During the Procedure of Hysteroscopy Sedated With Propofol，a Randomized, Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Endometritis
- Sponsor
- RenJi Hospital
- Enrollment
- 960
- Locations
- 1
- Primary Endpoint
- The incidence of hypoxia
- Last Updated
- 4 years ago
Overview
Brief Summary
To determine whether high-flow nasal cannula oxygen can reduce the incidence of hypoxia during the procedure of sedated hysteroscopy.
Investigators
Eligibility Criteria
Inclusion Criteria
- •20 years old ≤ age ≤ 50 years old, female.
- •Undergoing hysteroscopy sedated with propofol for diagnosis or treatment.
- •Informed consent
- •ASA physical status Ⅰ\~ Ⅱ.
Exclusion Criteria
- •Epistaxis, nasal congestion and nasal mucosal damage.
- •Confirmed brain disease (cranial trauma, tumor, stroke, cognitive dysfunction etc.).
- •Confirmed severe heart disease (heart failure, angina pectoris, myocardial infarction, arrhythmia, etc.).
- •Confirmed severe lung diseases (upper respiratory tract infection, asthma, bronchitis, COPD, bullae, pulmonary embolism, pulmonary edema, lung cancer, etc.).
- •Pregnant women.
- •Acute and chronic hepatitis or liver cirrhosis with severe abnormal liver function.
- •Acute and chronic nephritis with severe abnormal renal function or renal failure.
- •Needing oxygen inhalation for underlying diseases.
- •Emergency surgery.
- •Combined with multiple trauma.
Outcomes
Primary Outcomes
The incidence of hypoxia
Time Frame: Patients will be followed for the duration of hospital stay, an expected average of 2 hours
75%≤SpO2\<90% and \<60S
Secondary Outcomes
- The incidence of sub-clinical respiratory depression(Patients will be followed for the duration of hospital stay, an expected average about 2 hours)
Study Sites (1)
Loading locations...
Similar Trials
Unknown
Not Applicable
HFNO Reduces Hypoxia During Sedated Gastroscopy or Colonoscopy in High Risk PatientsGastric CancerIntestinal CancerIntestine AdenomaGastritisNCT05510388RenJi Hospital450
Completed
Phase 4
Short Term Physiological Effects of Nasal High Flow Oxygen on Respiratory MechanicsCOPDChronic Hypercapnic Respiratory FailureNCT02363920IRCCS Azienda Ospedaliero-Universitaria di Bologna14
Unknown
Not Applicable
Effect of High Flow Nasal Cannula on Oxygenation During Urodynamic Study in Pediatric PopulationDesaturationNCT04152733Seoul National University Hospital82
Unknown
Not Applicable
Conduct of Nasal High Flow Oxygen in Acute Respiratory FailureAcute Respiratory Failure With HypoxiaHypoxemiaNCT03311087Hôpital Louis Mourier100
Completed
Not Applicable
Impact of Prophylactic High Flow Nasal Oxygen in Post-Operative Thoracic Surgical PatientsPost-operative Pulmonary ComplicationsNCT03024112University of Colorado, Denver51