Impact of Prophylactic High Flow Nasal Oxygen in Post-Operative Thoracic Surgical Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Post-operative Pulmonary Complications
- Sponsor
- University of Colorado, Denver
- Enrollment
- 51
- Locations
- 1
- Primary Endpoint
- Number of Participants With Post-operative Pulmonary Complications
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
The Investigators goal was to study the effect of high flow nasal cannula oxygen (HFNC) on the rate of post-operative pulmonary complications in thoracic surgical patients. The Investigators hypothesis is that prophylactic HFNC oxygen, as compared to standard oxygen treatment, will reduce the incidence of postoperative pulmonary complications, improve post-operative pulmonary function, and reduce Intensive Care Unit (ICU) and hospital length of stay.
Detailed Description
The Investigators goal was to study the effect of high flow nasal cannula oxygen (HFNC) on the rate of post-operative pulmonary complications in thoracic surgical patients. The Investigators hypothesis is that prophylactic HFNC oxygen, as compared to standard oxygen treatment, will reduce the incidence of postoperative pulmonary complications, improve post-operative pulmonary function, and reduce ICU and hospital length of stay.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Undergoing Thoracic surgery
- •Planned admission to ICU after surgery
Exclusion Criteria
- •Younger than 18
- •Breast feeding
- •Known diagnosis of obstructive sleep apnea
- •Current or previous lung transplant
- •Pneumonectomy
- •Home oxygen greater than 4L/minute
- •Inability to adhere to assigned treatment prior to 48 hours of surgery or until transferred to a floor
Outcomes
Primary Outcomes
Number of Participants With Post-operative Pulmonary Complications
Time Frame: 30 days
The primary outcome "post-operative pulmonary complication" is defined as present if any one of the following criteria are met: * SpO2 \< 90% with FiO2 ≥ 50% * Dyspnea at rest * Respiratory rate \> 25 breaths/min * Active use of accessory respiratory muscles * PaO2/FiO2 ratio \< 200 * Escalation of therapy to non-invasive ventilation * Re-intubation * Occurrence of hospital-acquired pneumonia * Re-admission to the ICU
Secondary Outcomes
- ICU Length of Stay(30 days)
- Hospital Length of Stay(30 days)
- Lowest Oxygen Saturation Level Measured(30 days)