The Effects of High-flow Nasal Oxygen on Oxygenation During Rigid Bronchoscopy Under General Anesthesia in Pediatric Patients: A Prospective Observational Pilot Study
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Hypoxia occurs the first time
研究概览
简要总结
The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on maintenance of oxygenation and removal of carbon dioxide during apnoeic period in pediatric patients undergoing general anesthesia with rigid bronchoscopy
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 7 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing general anesthesia with stent placement or bougination, biopsy or removal of a foreign body or a mass through a rigid bronchoscope
- •Patients aged 7 or younger who meet American Society of Anesthesiologists (ASA) physical class 2-4
排除标准
- •Patients undergoing extracorporeal membrane oxygenation (ECMO)
- •Patients with active nasal bleeding), severe nasal obstruction, recent nasal trauma of surgery
- •Patients with current maxillofacial trauma or basal skull fracture
- •Patients with active nasal bleeding), severe nasal obstruction, recent nasal trauma of surgery
- •Extremely low birth weight infant and premature infant less than 28 weeks gestation age
- •Patients who had previously undergone rigid bronchoscopy / surgery
- •If the parent of subject includes a person who can not read the written consent (eg, illiterate, foreigner, etc.)
结局指标
主要结局
Hypoxia occurs the first time
时间窗: The time taken to reach the point at which peripheral oxygen saturation fell below 90% for the first time immediately after the onset of apnea intraoperatively.
The time taken to reach the point at which peripheral oxygen saturation fell below 90 for the first time immediately after the onset of apnea
the lowest oxygen saturation
时间窗: apnea period during the rigidbroscopic procedure/surgery
the lowest value of oxygen saturation measured percutaneously at extremity.
Occurence of hypoxic event
时间窗: apnea period during the rigidbroscopic procedure/surgery
Occurence of hypoxic event: Presence or absence of hypoxia(peripheral oxygen saturation fell below 90% ) during rigid bronchoscopy
次要结局
- End-tidal carbon dioxide partial pressure(end-tidal CO2 partial pressure after 3 consecutive breaths after intubation or insertion of laryngeal mask following end of apnea during intraoperative period.)
- Arterial oxygen / carbon dioxide partial pressure(shortly before start of apnea (within 30 seconds) and shortly after end of apnea (within 30 seconds))