High Flow Nasal Cannula Compared to Standard Oxygen for Endoscopic Ultrasound

Not Applicable

Not yet recruiting

• Conditions: Endoscopic Ultrasound

• Registration Number: NCT06704867
• Lead Sponsor: Mayo Clinic

Brief Summary

The purpose of the study is to evaluate the use of high flow nasal cannula versus standard oxygen therapy for high-risk patients undergoing endoscopy procedures.

Detailed Description

Patients with a higher BMI are at greater risk for lower oxygen levels which can delay the endoscopy procedure. This research is being conducted to find out if high risk patients will have a shorter recovery time and improved procedural conditions with a high flow nasal cannula versus standard oxygen therapy.

Study Timeline

• Study First Submitted: 2024-11-20
• Study First Submitted QC: 2024-11-25
• Study First Posted: 2024-11-26
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-15
• Last Update Posted: 2025-04-18
• Study Start: 2025-05-30
• Primary Completion: 2025-12
• Study Completion: 2026-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• All patients age 18 years and older who present to Gonda 2 procedural area for Endoscopic ultrasound (EUS) with or without endoscopy (EGD)/biopsy/tissue sampling. with BMI ≥ 35 kg/m2 (BMI within the past 6 months in electronic medical records or at current procedure) who are able to consent will be approached for potential enrollment.

Exclusion Criteria

• Need for general anesthesia for the procedure instead of the standard monitored anesthesia care.
• Patients undergoing combined procedure: Therapeutic EUS/combined procedures including EUS/ERCP, EUS/colonoscopy
• Patients on home oxygen therapy, or the diagnosis of "severe COPD"
• Patients with existing tracheostomy
• Inpatients undergoing EUS
• Inability to consent
• Cognitive impairment
• Blocked nasal passages
• Trauma/previous surgery to the nasopharynx
• Irregularities of the nose, face, or airway such that HFNC cannot be properly fitted

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Decrease recovery time	4 hours	Time measured in minutes for participants to enter post anesthesia care until the nurse marks "ready for discharge" in the medical record.

Secondary Outcome Measures

Name	Time	Method
Improve procedural conditions	1 hour	Decreased number of times the procedure is paused or delayed.

Trial Locations

Locations (1)

Mayo Clinic; 🇺🇸 Rochester, Minnesota, United States