Chen-style Tai Chi in Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease

Laval University1 site in 1 country44 target enrollmentMarch 2014

ConditionsChronic Obstructive Pulmonary Disease (COPD)

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Sponsor: Laval University
Enrollment: 44
Locations: 1
Primary Endpoint: Change from baseline dyspnea at 12 weeks
Status: Completed
Last Updated: 8 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This study will evaluate the effects of Chen-style Tai Chi compared to conventional exercise in pulmonary rehabilitation for COPD patients. Half of participants will receive the Chen-style Tai Chi intervention, while the other half will receive the conventional exercise intervention. Both groups will receive the same eduction and support during pulmonary rehabilitation.

Registry

clinicaltrials.gov

Start Date

March 2014

End Date

July 1, 2017

Last Updated

8 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Laval University

Responsible Party

Principal Investigator

Louis Gendron

MSc

Laval University

Eligibility Criteria

Inclusion Criteria

•FEV1 between 30 and 80% of the predicted normal values
•FEV1/FVC ratio \< 70%

Exclusion Criteria

•Patients with very severe COPD (GOLD IV);
•Patients that had a COPD exacerbations within the preceding 2 weeks of the baseline assessments;
•Significant hypoxemia at rest or during exercise (SpO2 \<85%);
•Already following a rehabilitation program;
•Have physical limitations that compromises participation to a Tai chi and a conventional exercise program

Outcomes

Primary Outcomes

Change from baseline dyspnea at 12 weeks

Time Frame: Baseline, 12 weeks

Dyspnea will be assessed using the chronic respiratory questionnaire (CRQ)

Secondary Outcomes

Change from baseline lung function at week 12 (Spirometry and whole-body plethysmography)(Baseline, 12 weeks)
Change from baseline of composite serum and plasma biomarkers at 12 weeks(Baseline, 12 weeks)
Change from baseline isokinetic quadriceps muscle function at 12 weeks(Baseline, 12 weeks)
Change from baseline physical activity at 12 weeks (participants will be equipped with a physical activity monitor)(Baseline, 12 weeks)
Change from baseline health status at 12 weeks (determined with the COPD Assessment test (CAT).(Baseline, 12 weeks)
Change from baseline exercise capacity at 12 weeks(Endurance time during a constant work rate bicycle ergometry exercise test)(Baseline, 12 weeks)
Change from baseline balance (Berg Balance Test (BBT) at 12 weeks(Baseline, 12 weeks)
Change from baseline walking distance at 12 weeks (distance walked during the six-minute walk test)(Baseline, 12 weeks)
Change from baseline isometric quadriceps muscle strength at 12 weeks (force of the dominant quadriceps will be measured during a single magnetic stimulation of the femoral nerve)(Baseline, 12 weeks)
Change from baseline quality of life (QoL) at 12 weeks(Baseline, 12 weeks)