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Identification of the sentinel lymph node (SLN) in patients with colon carcinoma.

Phase 1
Conditions
Colon carcinoma
Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Investigative Techniques [E05]
Registration Number
EUCTR2021-006700-32-NL
Lead Sponsor
Meander Medical Centre
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Authorised-recruitment may be ongoing or finished
Sex
All
Target Recruitment
5
Inclusion Criteria

- Oral and written informed consent (IC)
- Aged 18 years and older
- Pathologically confirmed and/or suspected cT1-3N0-2M0 colon carcinoma
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 2
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range 3

Exclusion Criteria

- Distant metastasis
- Suspicion of cT4 disease based on pre-operative assessment
- Metastatic or T4 disease discovered during intraoperative staging
- Pregnancy, lactation or a planned pregnancy during the course of the
study
- Previous colon surgery, excluding appendectomy.
- Contra-indication for laparoscopic/robotic surgery
- Inadequately controlled hypertension with or without current antihypertensive medication.
- Within 6 months prior to inclusion: myocardial infarction, TIA, CVA, pulmonary embolism, unstable angina pectoris, or uncontrolled chronic hepatic failure.
- Regarding bevacizumab: Hypersensitivity to Chinese Hamster Ovary
(CHO) cell products or other recombinant human or humanised
antibodies. Or an allergy for its components (Trehalose dehydrate,
sodium phosphate, polysorbate 20, water for injections)

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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