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临床试验/NCT05466305
NCT05466305Unknown不适用

Immunological and Microbiological Assessment of Maxillary Acrylic Resin Complete Dentures Reinforced by Gold Plated Cr-Co Palatal Plate

Badr University0 个研究点目标入组 12 人开始时间: 2022年8月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
12
主要终点
Immunological assessment using Salivary IgA level through ELISA test

研究概览

简要总结

Gold is widely used in prosthetics. Its use ranges from being employed in the fabrication of removable dentures, where the inner surface permanently touching oral cavity tissues, through to fixed dentures, and even some structures of certain implantological systems. All such items can be made of galvanized gold. Thus, new technologies have made gold and its alloys a kind of a universal material.

详细描述

Gold is widely used in prosthetics. Its use ranges from being employed in the fabrication of removable dentures, where the inner surface permanently touching oral cavity tissues, through to fixed dentures, and even some structures of certain implantological systems. All such items can be made of galvanized gold. Thus, new technologies have made gold and its alloys a kind of a universal material.

Using metal alloys (gold alloys included) to make the framework for removable dentures is much better than using acrylic resin. This because the alloys have almost no destructive influence over the dentures bearing area. Due to the precise way it is made, the stability of shape, the lack of internal stresses and the close contact with the dentures bearing area, it is possible to achieve very good retention of the denture over a long span of time. Another advantage is that the metal framework conducts temperature changes and this facilitates keeping the tissues in good health. Also, a denture metal framework makes it much easier for the patient to maintain good oral hygiene by lowering the risk of plaque accumulation. However, a metal framework has a disadvantage as well - prosthesis relining cannot be made.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Single (Participant)

入排标准

年龄范围
4 Years 至 65 Years(Child, Adult, Older Adult)
性别
Male
接受健康志愿者

入选标准

  • Completely edentulous maxillary and mandibular ridges
  • Healthy mucosa and absence of remaining roots
  • Good physical and mental health
  • Willing to give informed consent
  • Normal maxilla-mandibular relationship Angle Class I
  • Adequate bone quality and quantity in terms of width and height in the anterior maxillary mandibular ridges verified by preoperative cone beam CT
  • Adequate inter-arch space to accommodate maxillary and mandibular implant prostheses

排除标准

  • Uncontrolled diabetes
  • Smoking habits
  • Radiotherapy
  • Clinical or radiographic signs of pathologic conditions
  • Osteoporosis
  • Patients on corticosteroids

结局指标

主要结局

Immunological assessment using Salivary IgA level through ELISA test

时间窗: 45 days

Immunological assessment of maxillary complete denture reinforced by gold plated Cr-Co alloy

次要结局

  • Microbiological assessment using Staphylococcus Aureus, Staphylococcus Epidermis and Candida Albicans Colonization(45 days)

研究者

发起方
Badr University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Shady El Naggar

Clinical Professor

Badr University

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