Effects of High and Low Frequency TENS on Sympathetic Skin Response and Skin Temperature

Not Applicable

Completed

• Conditions: Effects of TENS on Sympathetic Skin Response
• Interventions: Device: transcutaneous electrical nerve stimulation

• Registration Number: NCT01696149
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

The aim of this study was to determine the effects of 4 Hz and 110 Hz transcutaneous electrical nerve stimulation on the sympathetic nervous system via measuring the sympathetic skin response (SSR) and skin temperature.

Detailed Description

15 healthy subjects (8 females, 7 males) with a mean age of 22.6 ± 3.7 years participated in this study.

All subjects participated, randomly, in a 4 Hz TENS session, a 110 Hz TENS session, and a control (off-TENS) session. Each session consisted of a 20- minute stimulation period and a 10-minute follow up period.

Outcome measures: Sympathetic skin response from the simulated (Right) hand and skin temperature of both stimulated (Right) and none stimulated (Left) hand was measured 15 seconds before, just 15 seconds after, and 10 minutes after application of interventions.

Study Timeline

• Study Start: 2010-03
• Primary Completion: 2011-02
• Study Completion: 2011-06
• Status Verified: 2012-09
• Study First Submitted: 2012-09-18
• Study First Submitted QC: 2012-09-27
• Last Update Submitted: 2012-09-27
• Study First Posted: 2012-09-28
• Last Update Posted: 2012-09-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• Men and women aged 18 to 30 years

Exclusion Criteria

• History of cardiovascular, neurologic or musculoskeletal disease
• Taking medication at the time of the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
electrical nerve stimulation	transcutaneous electrical nerve stimulation	All subjects participated, randomly, in a 4 Hz transcutaneous electrical nerve stimulation session, a 110 Hz transcutaneous electrical nerve stimulation session, and a control (off-transcutaneous electrical nerve stimulation) session. Each session consisted of a 20- minute stimulation period and a 10-minute follow up period

Primary Outcome Measures

Name	Time	Method
Changes of sympathetic skin response	15 seconds before, just 15 seconds after, and 10 minutes after application of interventions	Sympathetic skin response from the simulated (Right) hand was measured 15 seconds before, just 15 seconds after, and 10 minutes after application of interventions.

Secondary Outcome Measures

Name	Time	Method
Changes of skin temperature	15 seconds before, just 15 seconds after, and 10 minutes after application of interventions	skin temperature of both stimulated (Right) and none stimulated (Left) hand was measured 15 seconds before, just 15 seconds after, and 10 minutes after application of interventions