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Clinical Trials/NCT04507399
NCT04507399CompletedNot Applicable

Investigating Consumers Perception and Acceptance of Whey Beverages

University of Reading1 site in 1 country40 target enrollmentStarted: August 6, 2020Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
40
Locations
1
Primary Endpoint
Mucoadhesion and Mouthdrying

Study Overview

Brief Summary

Brief Summary: This study aims to investigate whether protein fortification of beverages causes mouthdrying and mucoadhesion and whether this is influenced by saliva flow.

Detailed Description

To investigate whether whey protein beverages causes mouthdrying and reduces acceptability compared with a control beverage (whey permeate beverage) and to determine whether manipulating salivary flow rates influences mouthdrying.

To determine whether mucoadhesion is a probable cause of mouthdrying.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover
Primary Purpose
Other
Masking
Single (Participant)

Eligibility Criteria

Ages
18 Years to 30 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •No food allergies or intolerances
  • •Non smokers

Exclusion Criteria

  • •Taking prescribed medication that could influence study outcomes (such as saliva flow)
  • •Relevant food allergies or intolerances
  • •Outside age criteria
  • •Had oral surgery or a stroke
  • •Anyone who currently has COVID-19 symptoms or who has had COVID-19 within the last 4 weeks

Arms & Interventions

Protein Beverage

Experimental

Whey Protein Beverage

Intervention: Liquid Model (Behavioral)

Control Beverage

Experimental

Whey Permeate Beverage

Intervention: Liquid Model (Behavioral)

Outcomes

Primary Outcomes

Mucoadhesion and Mouthdrying

Time Frame: Saliva collection and mouthdrying scoring throughout visits, 2 days

Following swallowing of different whey beverage samples (whey protein / whey permeate), volunteers will be asked either to rate samples for mouthdrying or to spit their saliva into a tube at specific timepoints (15s \& 60s) with appropriate rest periods. The rating and spitting times will be set within a balanced order protocol.

Secondary Outcomes

  • Mouthdrying from whey beverages(1 day (Sampled at study visit one))
  • Manipulating saliva flow and mouthdrying from whey beverages(1 day (Sampled at study visit one))
  • Saliva collection(1 day (Sampled at study visit two))

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Lisa Methven

Head of Sensory Science

University of Reading

Study Sites (1)

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