Eye-tracking parameters as biomarkers of frontotemporal dementia

• Conditions: 10042258; Alzheimer's disease; Frontotemporal dementia

• Registration Number: NL-OMON51509
• Lead Sponsor: eurologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 136

Inclusion Criteria

1) Patients with FTD referred to our referral center and diagnosed with use of
International
Consensus Criteria. The dementia symptoms have to be mild (clinical dementia
rating <=1). Patients with all variants of FTD (behavioural frontotemporal
dementia, semantic variant PPA, non-fluent variant PPA) will be included.
2) Patients with mild Alzheimer's dementia diagnosed according to International
Consensus Criteria. The dementia has to be mild (clinical dementia rating <=1).
3) Asymptomatic, first degree relatives of dementia patients due to genetic
mutations. They have 50% chance of having the mutation and developing FTD. DNA
status is determined in a related study (MEC-2009-409) in a double-blind
design. Participation is possible from 18 years and over.

Exclusion Criteria

Subjects with a previous stroke or other (neurological) conditions that may
affect cognitive functions (brain tumour, multiple sclerosis, use of
psycho-active medications) will be excluded from participation in this study.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Eye movement features derived from the eye-tracking test battery. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable</p><br>