Coffee Trial - Does Coffee Intake Reduce Postoperative Ileus After Elective Colectomy?

Not Applicable

Completed

• Conditions: Colectomy
• Interventions: Other: Postoperative coffee; Other: water

• Registration Number: NCT01079442
• Lead Sponsor: Heidelberg University

Brief Summary

The purpose of the investigators study is to investigate the effects of coffee on the return of bowel function and appetite, length of hospital stay, and complications after elective open colectomy in a prospective randomized trial. The primary efficacy endpoint is time to first bowel movement.

Detailed Description

Coffee is a popular beverage. Its effects on general well being, central nervous system and cardiovascular system are well known, but there is limited information regarding its effects on gastrointestinal function.

Study Timeline

• Study Start: 2010-03
• Study First Submitted: 2010-03-01
• Study First Submitted QC: 2010-03-02
• Study First Posted: 2010-03-03
• Primary Completion: 2011-03
• Study Completion: 2011-03
• Status Verified: 2011-09
• Last Update Submitted: 2011-09-29
• Last Update Posted: 2011-09-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Patients scheduled for elective open or laparoscopic colectomy
• Age equal or greater than 18 years
• Informed consent

Exclusion Criteria

• Participation in concurrent intervention trials
• Need for a stoma
• Known hypersensitivity or allergy to coffee
• Expected lack of compliance
• Impaired mental state or language problems
• change in surgical procedure

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Treatment arm: coffee	Postoperative coffee	coffee administration
Water arm	water	The control drink consists of 100 ml warm water

Primary Outcome Measures

Name	Time	Method
Time to first bowel movement	patients postoperative in hospital stay (mean 6 days)	Time from end of surgery until patient's first bowel movement (i.e. passage of stool).

Trial Locations

Locations (3)

Salem Krankenhaus; 🇩🇪 Heidelberg, Germany

Kreiskrankenhaus GRN Sinsheim; 🇩🇪 Sinsheim, Germany

University hospital; 🇩🇪 Heidelberg, Germany