Effects of Preoperative Coffee Consumption in Cesarean Sections Under Spinal Anesthesia

Completed

• Conditions: Hypotension After Spinal Anesthesia; Post-Dural Puncture Headache
• Interventions: Other: Water; Other: coffee

• Registration Number: NCT05262933
• Lead Sponsor: TC Erciyes University

Brief Summary

The prospective study is planned in a university hospital. Spinal anesthesia is widely used for cesarean section currently for its safety, low cost, reliability, easiness to administer, immediate effect, and well-operating conditions. However spinal anesthesia has some complications as hypotension, bradycardia and Post Dural Puncture Headache (PDPH). A practical strategy for avoiding hypotension during initiation of spinal anesthesia for cesarean delivery includes intravenous crystalloid, in conjunction with administration of vasopressors. PDPH is one of the most frequent complications of spinal anesthesia. Conservative therapies such as bed rest, hydration, and caffeine are commonly used as management. For this study, coffee group of patients will be given unsweetened brewed coffee 150 ml until 2-4 hours before surgery. Patients who accept to drink brewed coffee ( coffee group) and water( control group) will be included in the study. The patient's heart rate, blood pressure, oxygen saturation will be monitored and recorded during operation. Intraoperative will be recorded to amount of vasopressor and intraveous crystalloid. Whether the patient develops PDPH in the postoperative period will be followed for 3 days. In addition abdominal auscultation for bowel sounds hourly and the time of first bowel movements will be recorded. According to the patient's statement, the time of first flatulence and defecation will be followed and recorded.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-02-21
• Study First Submitted QC: 2022-02-21
• Study First Posted: 2022-03-02
• Study Start: 2022-03-15
• Primary Completion: 2022-06-01
• Study Completion: 2022-07-01
• Status Verified: 2024-05
• Last Update Submitted: 2024-05-14
• Last Update Posted: 2024-05-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 2

Inclusion Criteria

• patients who accept to participate in the study
• patient who limit the consumption of caffeinated beverages such as coffee and tea during pregnancy
• Patients with known caffeine or coffee allergy

Exclusion Criteria

• patients who refuse to participate in the study
• Patients with known cardiovascular disease
• Patients with known cerebrovascular disease
• patients with known neurological, neurodegenerative or psychiatric disease
• patients with known liver failure
• patient followed up with eclampsia and preaclampsi
• higher number of needle passes in spinal anesthesia
• patients treated with an antiemetic

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
control (n=70)	Water	Patients are planned to drink water 2 hours before surgery.
coffee (n= 70)	coffee	Patients are planned to drink brewed coffee 2 hours before surgery.

Primary Outcome Measures

Name	Time	Method
hypotension	intraoperative time period	effects of orally coffee intake on spinal anesthesia induced hypotension

Secondary Outcome Measures

Name	Time	Method
Post-dural puncture headache	post operative 3 days	Effects of orally coffee intake on postdural puncture headache
intestinal motility, first flatus	post operative 3 days	Effects of orally coffee intake on postoperative intestinal motility

Trial Locations

Locations (1)

Erciyes University; 🇹🇷 Kayseri, Turkey