Hemodynamic Effects of Negative Pressure Ventilation in Chronic Obstructive Pulmonary Disease Assessed Using Non-Invasive Electrical Cardiometry
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- CO (cardiac output)
研究概览
简要总结
Negative pressure ventilation (NPV) is a non-invasive ventilation mode which provide better lung expansion. The major complication of NPV is decrease blood pressure and affects the hemodynamics. The effects of NPV on chronic obstructive pulmonary disease (COPD) patients with pulmonary rehabilitation program remains unknown.
详细描述
Both of NPV or positive pressure ventilation (PPV) has impact of hemodynamics. NPV with cuirass ventilator increases venous return and leads to ventricular filling and increases cardiac output (CO); In contrast to NPV, the effect of PPV in most situations is a decreased venous return and leads to decreased CO. NPV improving ventilation and work of breathing in patients with chronic obstructive pulmonary disease (COPD).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with COPD who received pulmonary rehabilitation program with NPV treatment
排除标准
- •Recent exacerbation within 3-months
- •Existing of tracheostomy
- •Absence of NPV used
- •Required of oxygen supplement during NPV
- •Diagnosed of neuromuscular disease
结局指标
主要结局
CO (cardiac output)
时间窗: 20 minutes
Change of Cardiac output before and after NPV treatment
SV (stroke volume)
时间窗: 20 minutes
Change of stroke volume before and after NPV treatment
次要结局
- SpO2(20 minutes)
- RR (respiratory rate)(20 minutes)
研究者
Ke-Yun, Chao
Head of Respiratory Therapist
Fu Jen Catholic University