Psychological Effects of Helicopter Pylori Associated Gastritis in Patients Attending Assiut University Hospitals

One of the most prevalant chronic bacterial illness affecting people is it H.plyori infection. it affects at least 50% of people worldwide . it is a human gastrointestinal infection which is believed to be blammed for a number of gastric illness from chronic gastritis up to gastric cancer.

numerous literature data suggest there is strong relation of anxiety disorders, stress or depression to somatic symptoms and this relation can undergo potentialization in case of appearance of pathogenic factors like helicobacter pylori infection , this relation can confirmed with many scientific reports , with the common use of antidepressants and anxiety relieving drugs in duodenal ulcer disease therapy.

The close relationship of gastrointestinal function with brain function and the mental status is known as (gut brain axis).

it has been reported that emotional factors induce changes in gastric physiology that physiological stress induces personality dependant gastric acid secretion changes and avariety of alterations in gastric motility.

. the effect of numerous stress factors which injury mucosa of stomach and modify immunity of the patient so that the patient become more sensitive to be infected with H. Pylori and infection become more aggressive and lead to manifestation of gastritis , duodenitis and gastric ulcer disease.