Does luteal estradiol supplementation have a role in long agonist cycles?

Completed

• Conditions: Infertility; Reproductive Health and Childbirth - Fertility including in vitro fertilisation

• Registration Number: ACTRN12608000225314
• Lead Sponsor: Eman Amin Elgindy

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-05-01
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 270

Inclusion Criteria

Women undergoing intracytoplasmic sperm injection due to male factor of infertility using pituitary desensitization by GnRH agonist long protocol

Exclusion Criteria

Age > 37 years, body mass index (BMI) < 18 or > 29, irregular menstral cycles, women with single ovary, day 3 serum follicle stimulating hormone (FSH) 9.5 milli international units (mIU)/ml or more, basal antral follicle count 6 or less, 5 or less retreived mature follicles, non availability of good quality embryos and failure to obtain a written consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical pregnancy by assessing clinical pregnancy rate[Human chorionic gonadotrophin (hCG) testing on day 16 and 18 after ET, Ultrasound 3 weeks after +ve hCG testing]

Secondary Outcome Measures

Name	Time	Method
uteal serum estradiol and progesterone levels by electrochemiluminescence immunoasays[Day of human chorionic gonadotropin (hCG) administration (day 0), +7, +10 and +13]