Evaluation of the relationship between AGEs and treatmentresponsiveness of anti-VEGF in DME patients’
- Conditions
- diabetic retinopathy (DR)
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 70
Inclusion Criteria
Patients diagnosed with DME who started inravitreal anti-VEGF therapy less than 1 yr ago
· Age: >18 years.
Exclusion Criteria
Dark coloured skin (Fitzpatrick type V or VI).
· Skin abnormalities on both arms that will impair the reliability of the autofluorescence
measurement.
· Local or general active infection or inflammatory disease.
· Known renal disease, current dialysis treatment, or a history of renal transplantation.
· Patients with high myopia (>6 diopters), glaucoma, combined retinal disease, media
opacities interfering with OCT imaging, vitreomacular traction on SD-OCT and those
whose SD-OCT images were of poor quality, intraocular surgery within 12 weeks prior
to the first injection
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method