Evaluation of the relationship between AGEs and treatment outcome of vitrectomy in PDR patients

• Conditions: diabetes mellitus, diabetic retinopathy

• Registration Number: NL-OMON22139
• Lead Sponsor: niversity of Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 70

Inclusion Criteria

•Willingness to participate.
•Age: >18 years.
•Patients diagnosed with PDR who have undergone or will undergo vitrectomy at the UMCG.
•Patients who have at least 1-year follow-up with BCVA after vitrectomy at the UMCG will be included.

Exclusion Criteria

•Unwillingness to participate.
•Dark coloured skin (Fitzpatrick type V or VI), which will impair the reliability of the autofluorescence measurement.
•Skin abnormalities on both arms that will impair the reliability of the autofluorescence measurement.
•Local or general active infection or inflammatory disease.
•Known renal disease, current dialysis treatment, or a history of renal transplantation.
•Patients with high myopia (>6 diopters), glaucoma, combined retinal disease, prior vitreoretinal surgery.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
the relation between skin AF and visual outcome of PDR patients at 1 year after vitrectomy.<br>

Secondary Outcome Measures

Name	Time	Method
re-vitrectomy rate within the first year.<br>