The effect of moderate acidification of arterial blood pH on the rate of miR-499 Biomarker level in the early minutesafter aortic clamp opening during heart valve surgery: A Pilot Study
Not Applicable
Recruiting
- Conditions
- The effect of moderate arterial blood acidosis during reperfusion in valvular heart surgery.
- Registration Number
- IRCT20211101052940N2
- Lead Sponsor
- Shahid Rajaei Cardiovascular Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Patient consent to study
Age over 18 years and under 65 years
No history of sternotomy and heart surgery
Left ventricular ejection fraction greater than 30%
Pulmonary outflow volume with pressure per second (FEV1) greater than 65% in spirometry
Hemoglobin above 10 mg per deciliter
Exclusion Criteria
Need for drug support (receiving inotropes before starting heart surgery)
Having a pacemaker or ICD(Implantable Cardioverter Defibrillator)
Having impaired lung function tests for FEV1 less than 40%
Having kidney or liver dysfunction
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method