EUCTR2013-002037-38-NL进行中（未招募）不适用
The effect of correction of metabolic acidosis in chronics kidney disease on intrarenal RAS activity. - BIC study
未提供0 个研究点开始时间: 2013年7月30日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- male or female adult (>18 years)
- •- chronic kidney disease stage 4, i.e. eGFR (MDRD) 15-30 ml/min
- •- plasma bicarbonate concentration of <24 and >15 meq/L, the latter
- •because in that case it seems highly recommended to start
- •sodiumbicarbonate suppletion and not to postpone this
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 22
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 23
排除标准
- •- plasma bicarbonate level >24 meq/L or <15 meq/L
- •- sodiumbicarbonate use in the 1 month preceeding the study
- •- a kidney transplant in situ
- •- heart failure
- •- liver cirrhosis
- •- resistant hypertension (blood pressure >140/90 mmHg despite the use of 3 or more different antihypertensives
- •- a history of inadherence to medication
- •- use of calcineurin inhibitors (these immunosuppressive drugs are
- •known to induce metabolic acidosis and influence electrolytes and acidbase
研究者
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