Effect of correction of metabolic acidosis on respiration and hemodynamics in acute respiratory distress syndrome (ARDS) patients during mechanical ventilation: A randomized comparison of sodium bicarbonate and Tris-hydroxymethyl aminomethane (THAM).
Not Applicable
- Conditions
- acute respiratory distress syndrome (ARDS)
- Registration Number
- JPRN-UMIN000021756
- Lead Sponsor
- Osaka University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1. Patients under 18 years old 2. Patients of central nervous system (CNS) diseases with increased intracranial pressure 3. Female patients who are pregnant, lactating and with possibility of pregnant 4. Patients with artificial cardiopulmonary system 5. Other patients who are judged to be inappropriate for this study by research contact person.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Minute volume within six hours from start of administration
- Secondary Outcome Measures
Name Time Method pH, PaCO2, blood pressure, and heart rate within six hours from start of administration