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临床试验/NL-OMON48596
NL-OMON48596招募中不适用

The difference in postprandial anabolic response between young and elderly, healthy volunteers. - TOAST

Academisch Medisch Centrum0 个研究点目标入组 18 人开始时间: 待定最近更新:

试验速览

阶段
不适用
状态
招募中
入组人数
18

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • - Ability to provide informed consent
  • - 18-30 years or older than 65 years at the time of signing the informed consent
  • - Body mass index (BMI) 18.5- 25 kg/m2
  • - Caucasian men
  • - General good health as determined by medical history, physical examination
  • and blood chemistry by a physician.
  • - HOMA-IR index: * 2.0 (measured as fasting insulin (pmol/L) x fasting glucose
  • (mmol/L) / 135)

排除标准

  • - Major illness in the past 3 months
  • - Use of any medication
  • - Gastro-intestinal disease that may influence bile acid signalling metabolism
  • - History of cholecystectomy or other bile duct abnormalities
  • - Tobacco smoking
  • - Drugs abuse
  • - Alcoholism (>3 units a day)
  • - Blood chemistry (fasted):
  • * Creatinine >120 µM
  • * Glucose * 5.6 mmol/L
  • * >2 times upper limit reference interval of the following: ASAT, ALAT, GGT, AP
  • - Strenuous exercise for at least 3 days prior to each study day, defined as
  • more than 1 hour of exercise per day.
  • - Hypersensitivity to substances in Nutridrink

研究者

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