Combination of Spinal-Epidural With General Anesthesia in Patients Undergoing Mega-Liposuction Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- morphine consumption
研究概览
简要总结
The combination of general anesthesia to spinal and epidural techniques (CSEGA) proved to have a synergistic effect, thus, the use of sub-anesthetic doses can provide satisfactory anesthetic and analgesic results. CSEGA has several known advantages including appropriate postoperative analgesia, shows some benefit in the intraoperative blood loss control causing a decreased need for blood transfusion, rapid regain of the gastrointestinal actions and decreases the incidence of postoperative respiratory complications. Unfortunately, the drawbacks of using neuro-axial anesthesia in combination to general anesthesia will be not thoroughly introduced in many researches, thus, remain unclear.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Inclusion criteria:
- •Patients aged from 18 to50 years.
- •ASA I-II.
- •undergoing elective liposuction surgery
- •BMI from 25 to 40 kg/m2
排除标准
- •Patient refusal
- •ASA III-IV.
- •Patients aged less than 18 or more than
- •Body mass index >
- •Any contraindications to neuro-axial block such as coagulopathy or spine deformity
- •Chronic opioid consumption,
- •History of parenteral or oral analgesic intake within the last 48hours.
研究组 & 干预措施
CSEGA group
Will be received combined spinal-epidural-general anesthesia.
干预措施: spinal-epidural device (Device)
GA group
will be received general anesthesia only.
结局指标
主要结局
morphine consumption
时间窗: 24 hours
postoperative morphine consumption
次要结局
- Intraoperative surgeon satisfaction.(6 hours)
- Incidence of complications(24 hours)
- Blood loss(6 hours)
- Postoperative patient satisfaction(24 hours)
研究者
Amr Samir Wahdan
Lecturer of Anesthesia, Pain management and Surgical ICU
Cairo University