Immunity Improvement Effect of Ulmus Macrocarpa Water Extract in Adults
Phase 3
Completed
- Conditions
- Healthy
- Interventions
- Dietary Supplement: Ulmus macrocarpa water extract
- Registration Number
- NCT02414412
- Lead Sponsor
- Pusan National University Hospital
- Brief Summary
This randomized, placebo-controlled, double-blind study evaluates the efficacy and tolerability of Ulmus macrocarpa water extract for immunity improvement in relatively healthy adults. 58 subjects received 500 mg of Ulmus macrocarpa water extract per day or a placebo for 4 weeks.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 58
Inclusion Criteria
- subject has peripheral white blood cells between 4,000/Ul and 8,000/Ul
Exclusion Criteria
- History of renal disease
- History of diabetes mellitus
- History of immune disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo Ulmus macrocarpa water extract placebo 250mg orally 2 times a day for 4 weeks Ulmus Ulmus macrocarpa water extract Ulmus macrocarpa water extract 250mg orally 2 times a day for 4 weeks
- Primary Outcome Measures
Name Time Method serum natural killer cell activity 1 month
- Secondary Outcome Measures
Name Time Method peripheral white blood cell 1 month serum tumor necrosis factor-alpha level 1 month serum interferon-gamma 1 month serum interleukins(1betta, 2,4,8,10, and 12) 1 month