Immunity Improvement Effect of Ulmus Macrocarpa Water Extract in Adults

Phase 3

Completed

• Conditions: Healthy

• Registration Number: NCT02414412
• Lead Sponsor: Pusan National University Hospital

Brief Summary

This randomized, placebo-controlled, double-blind study evaluates the efficacy and tolerability of Ulmus macrocarpa water extract for immunity improvement in relatively healthy adults. 58 subjects received 500 mg of Ulmus macrocarpa water extract per day or a placebo for 4 weeks.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-02
• Primary Completion: 2015-03
• Study First Submitted: 2015-04-07
• Study First Submitted QC: 2015-04-09
• Study First Posted: 2015-04-10
• Study Completion: 2015-05
• Status Verified: 2015-10
• Last Update Submitted: 2015-10-30
• Last Update Posted: 2015-11-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 58

Inclusion Criteria

• subject has peripheral white blood cells between 4,000/Ul and 8,000/Ul

Exclusion Criteria

• History of renal disease
• History of diabetes mellitus
• History of immune disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
serum natural killer cell activity	1 month

Secondary Outcome Measures

Name	Time	Method
peripheral white blood cell	1 month
serum tumor necrosis factor-alpha level	1 month
serum interferon-gamma	1 month
serum interleukins(1betta, 2,4,8,10, and 12)	1 month