Audiovestibular Functions in Covid 19 Patients in Sohag Governate
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Sohag University
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- Basic audiological evaluation:
Study Overview
Brief Summary
There is evidence that up to 30% of COVID-19 patients was reported with neurological manifestations such as impaired consciousness, headache, and dizziness have been reported in COVID-19 patients in addition, olfactory and taste alterations are common symptoms in patients affected by COVID-19.This study will be conducted to evaluate the effect of the novel coronavirus on audio-vestibular functions in confirmed COVID19 patients.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 20 Years to 50 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Well educated patients Age: range between 20 to 50 years No previous history of hearing loss or otoneurologic disease
- •Well confirmed COVID 19 patients:
- •patients who were diagnosed with coronavirus from
- •symptoms: fever, cough, generalized malaise, dyspnea.
- •Laboratory finding: abnormalities have been observed in Complete blood count (CBC), high C-reactive protein and ferritin, elevated D-dimer.
- •Imaging: Chest CT scan: bilateral ground glass opacities, crazy paving, and consolidation.
- •nasopharyngeal swab for SARS-CoV-2 polymerase chain reaction testing (RT-PCR).
Exclusion Criteria
- •previous history of hearing loss or otoneurological disease
Outcomes
Primary Outcomes
Basic audiological evaluation:
Time Frame: 3 months after infection
Speech audiometry
Auditory evoked potentials
Time Frame: 3 months after infection
P300
Auditory evoked potentials:
Time Frame: 3 months after infection
Auditory brainstem response.
Effect on vestibular functions
Time Frame: 3 months after infection
Computerized Dynamic Posturography (CDP)
Secondary Outcomes
- Effect on cognitive functions(3 months after infection)
- Vestibular questionnaire(3 months after infection)
Investigators
Yasmeen Ali Mohamed
Principal investigator
Sohag University