Platelet Rich Plasma Testis
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- sperm present
研究概览
简要总结
Investigate the effect of intratesticular injection of autologous platelet rich plasma (PRP) on sperm retrieval rates and IVF outcomes in infertile men who already underwent a negative sperm retrieval. Currently, there is no alternative treatment after failed TESE. Prior series suggest that intratesticular PRP injections may improve TESE outcomes. We hope to determine whether PRP is an effective treatment for this patient population.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Men over the age of 18 diagnosed with NOA and at least one failed TESE, negative mapping or negative biopsy
排除标准
- 未提供
研究组 & 干预措施
Platelet rich plasma treatment arm
After consent in obtained, the patient will undergo a blood draw (12 tsp) to prepare the PRP infusion. The use of a centrifuge and an Arteriocyte Magellan kit are necessary for the PRP preparation. After injection of local anesthesia, PRP will be injected into each testicle.
干预措施: Platelet rich plasma (Biological)
结局指标
主要结局
sperm present
时间窗: 3 months after PRP injection
A TESE procedure will be performed to determine if sperm are present
次要结局
未报告次要终点
研究者
Michael Eisenberg
Principal Investigator
Stanford University