Beginning Early and Assertive Treatment for Methamphetamine Use Disorder

Not Applicable

Active, not recruiting

• Conditions: Methamphetamine Use Disorder
• Interventions: Behavioral: care navigation

• Registration Number: NCT06033365
• Lead Sponsor: Denver Health and Hospital Authority

Brief Summary

The overall goal of the study is to evaluate the effectiveness of a secondary prevention strategy implemented at a systems-level to prevent stimulant related overdoses.

Detailed Description

To date, a public health systems approach to enhance linkage and engagement in care for stimulant use disorders is lacking. This shortcoming arises in part from the lack of effective treatments for stimulant use disorders (StUD), the specific pathology of methamphetamine use, and gaps in epidemiologic knowledge related to methamphetamine use disorder. Unlike opioid use disorders, for which medications relieve dysphoric symptoms of acute withdrawal and prevent relapse, patients with StUD present to care with methamphetamine-induced psychosis and may be combative, agitated, and poorly insightful to their need for treatment. In response to community demands, our team at Denver Health recently established a pilot program, Beginning Early and Assertive Treatment for Methamphetamine Use Disorder (BEAT Meth), to protocolize the assessment and treatment of patients with methamphetamine-induced psychosis.The current research project aims to develop and conduct process and outcomes evaluations of a linkage intervention aimed at increasing continuation and engagement in treatment for stimulant use disorder.

Study Timeline

• Study Start: 2023-04-11
• Study First Submitted: 2023-04-25
• Study First Submitted QC: 2023-09-11
• Study First Posted: 2023-09-13
• Status Verified: 2024-08
• Last Update Submitted: 2025-02-03
• Last Update Posted: 2025-02-05
• Primary Completion: 2025-03-31
• Study Completion: 2025-03-31

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 192

Inclusion Criteria

• 18 years of age and older
• identified in the Denver Health healthcare system who have had a methamphetamine-related encounter at Denver Health

Exclusion Criteria

• unable to complete the interview in English
• intoxicated or impaired and unable to consent to participate in the project and/or respond to the interview
• currently under residential involuntary psychiatric or substance treatment order (i.e., mental health hold, emergency commitment, or short-term certification)
• received any type of substance use treatment at DHHA in the last 90 days
• planning to enter substance treatment
• unable to complete the research visits in the next 90 days

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intervention	care navigation	Dedicated care navigator to address social support needs

Primary Outcome Measures

Name	Time	Method
Number of participants who entered treatment for methamphetamine use disorder	within 30 of study enrollment	Treatment entry as defined as attendance at an outpatient addiction treatment appointment within 30 days of BEAT Meth discharge

Secondary Outcome Measures

Name	Time	Method
Number of participants who overdosed	through study completion, an average of 1 year	non-fatal overdose as self-reported and fatal overdose from medical examiner
Number of participants retained in treatment at 30 days	30 days	Retention in treatment at 30 days
Number of participants retained in treatment at 90 days	90 days	Retention in treatment at 90 days

Trial Locations

Locations (1)

Denver Health; 🇺🇸 Denver, Colorado, United States