The effect of perioperative crystalloid or colloid intravenous administration on postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy

Not Applicable

Completed

• Conditions: Diseases of the digestive system

• Registration Number: KCT0006607
• Lead Sponsor: Myongji Hospital

Brief Summary

In laparoscopic cholecystectomy, administration of colloid did not reduce the incidence and severity of PONV compared to crystalloid.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2020-02-01
• Last Update Posted: 5 October 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

The study included 18- to 65-year-old patients with American Society of Anesthesiologists physical status I, or II, who underwent elective laparoscopic cholecystectomy under general anesthesia from January 2019 to January 2021

Exclusion Criteria

The exclusion criteria were BMI > 30, a history of cardiovascular, liver or kidney disease, diabetes mellitus with uncontrolled or complications, coagulation disorders, preoperative renal insufficiency, emergency surgery, preoperative infection, current pregnancy or lactation period, NRS for severity exceeds 3 points even after 3 antiemetic, and relevant drug allergy to medication used in the protocol.

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
incidence of PONV over 24hours

Secondary Outcome Measures

Name	Time	Method
severity of PONV over 24hours;rescue antiemetic use over 24hours after surgery