Effect of pentoxifylline on urinary protein excretion reduction in diabetic nephropathy patients.

Phase 2

• Conditions: Condition 1: Non-insulin-dependent diabetes mellitust. Condition 2: Diabetic Nephropathy.; Non-insulin-dependent diabetes mellitus; Glomerular disorders in diabetes mellitus

• Registration Number: IRCT138901013596N1
• Lead Sponsor: research deputy of Ahvaz Jundishapur University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

inclusion: diabetic nephropathy with GFR more than 30 ml/min and proteinuria more than 150 mg/24h.
exclusion: pentoxifylline sensivity, congestion heart failur, uncontroled HTN, patients that recived new drug with antiprotein effect( non dihydropridine calcium channel blockers, sprinolacton,beta blockers, diuretics) during study.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proteinuria in diabets patients. Timepoint: 3 & 6 month later. Method of measurement: measure of protein in 24h urin collection by using colorimetry.

Secondary Outcome Measures

Name	Time	Method
Pentoxifylline complications. Timepoint: monthly. Method of measurement: checklist & phisical exam.;Measure of GFR. Timepoint: monthly. Method of measurement: Cockcroft- Gault.;Measure of serum potasium. Timepoint: monthly. Method of measurement: flame photometry.