The effect of added buspiron to atypical antipsychotic drugs in the treatment of negative symptoms in patients with schizophrenia
Phase 2
- Conditions
- schizophrenia.schizophrenia
- Registration Number
- IRCT2017010431626N2
- Lead Sponsor
- Vice chancellor for research Ahvaz Jundishapur University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Inclusion Criteria: Age between 18 and 65 years old; Having schizophrenia according to DSM-VI-TR criteria; Bold negative symptoms( PANSS negative symptom sub-scale score more than 15); Disease duration of more than six months
Exclusion criteria: Bipolar disorders; Depression and other psychiatric disorders; Chronic medical conditions (liver, kidney and heart); A history of sensitivity to antipsychotics or buspirone; A history of failure to respond to treatment with adequate doses of antipsychotic medication; History of seizures; Pregnancy; Breastfeeding; Any disruption in the electrocardiogram; Simultaneous treatment with other drugs and active suicidal thoughts
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method egative symptoms. Timepoint: Before intervention, Three and six weeks after intervention. Method of measurement: PANSS questioner.
- Secondary Outcome Measures
Name Time Method