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Study to evaluate persistence of antibodies after vaccination with meningococcal vaccine GSK 134612

Phase 3
Registration Number
CTRI/2009/091/000585
Lead Sponsor
GlaxoSmithKline Biologicals
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
697
Inclusion Criteria

Subjects who the investigator believes that they and/or their parent(s)/guardian(s) can and will comply with the requirements of the protocol should be enrolled in the study.

A male or female having been vaccinated with a meningococcal vaccine in the primary study 109069.

Written informed consent obtained from parent(s)/guardian(s) of the subject and written informed assent obtained from the subject if the subject is less than 18 years of age, or written informed consent obtained from the subject if the subject has achieved the 18th birthday.

Healthy subjects as established by medical history and clinical examination before entering into the study.

Exclusion Criteria

Use of any investigational or non-registered product (drug or vaccine) within 30 days preceding the subject?s first visit.
History of meningococcal disease; such cases will be documented.
Administration of a meningococcal polysaccharide or a meningococcal polysaccharide conjugate vaccine since previous vaccination in study 109069.
Any confirmed or suspected immunosuppressive or immunodeficient condition, based on medical history.
Administration of immunoglobulins and/or any blood products within the three months preceding the subjects first visit.
Bleeding disorders, such as thrombocytopenia, or subjects on anti-coagulant therapy
Subjects who withdrew consent to be contacted for follow-up studies.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Persistence of immunogenicity with respect to components of the investigational vaccineTimepoint: 24, 36, 48 and 60 months post primary dose
Secondary Outcome Measures
NameTimeMethod
Persistence of immunogenicity with respect to components of the investigational vaccine (on secondary readouts)Timepoint: 24, 36, 48 and 60 months post primary dose
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