Effects of Combination Therapy of Baclofen & Trihexyphenidyl on Spasticity in Brain Injury Patients

Phase 2

• Conditions: Spasticity in Post Traumatic Brain Injury Patients.; G80.3; Dyskinetic

• Registration Number: IRCT20200415047096N1
• Lead Sponsor: Kerman University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 October 2020

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Early Onset Spasticity in Post Traumatic Brain Injury Patients

Exclusion Criteria

The level of consciousness (GCS) is equal to 3 out of 15
Severe drug side effects following baclofen or Trihexyphenidyl
History of severe allergy to baclofen or Trihexyphenidyl

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Spasm in the muscles of the wrist flexor muscles on one side. Timepoint: Spasm in the flexor muscles of the wrist on one side (left hand) is recorded on First day, third day, seventh day, first month, third month, and sixth month after administration. Method of measurement: Modified Ashworth Scale.