Comparison of the effect of drug combination in lower back anesthesia on duration of effect and changes in heart rate and blood pressure in patients undergoing orthopedic surgery with lower limb fractures

Phase 3

• Conditions: ower Limb fracture.; Disorder of bone, unspecified; M89.9

• Registration Number: IRCT20170413033408N3
• Lead Sponsor: Gorgan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 15 June 2020

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Patient with lower limb fracture candidate for orthopedic surgery which can be performed under spinal anesthesia
Signing a consent form
Class 1 or 2 of the physical condition of the American Anesthesia Association ASA
Age range 18-60 years
Elective surgery

Exclusion Criteria

High intracranial pressure
Infection in site of injection
Impossible of proper position
History of allergy with bupivacaine or pethidine

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The duration of the anesthetic effect. Timepoint: The duration of anesthesia will be recorded every minute immediately after intravenous injection until the onset of sensory block and every 5 minutes until sensory level stabilization. Method of measurement: Using a blunt needle and register in the checklist.;Hemodynamic change. Timepoint: Hemodynamic changes in the operating room will be measured every 5 minutes until the end of the first 30 minutes, then every 15 minutes until the end of surgery. The recovery room will record every 15 minutes until recovery criteria are met. Method of measurement: Hemodynamic criteria (heart rate, systolic, diastolic, and mean arterial blood pressure (MABP), arterial oxygen saturation) of the patient will be measured by Saadat monitoring.