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Clinical Trials/NCT05884164
NCT05884164
Completed
Not Applicable

Comparative Study: Erector Spinae Plane Block Versus Paravertebral Plane Block Regarding Their Effect on Peri-operative Opioid Consumption in Patients Undergoing Minimally Invasive Mitral Valve Replacement .

Ain Shams University1 site in 1 country80 target enrollmentMarch 24, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
ERAS
Sponsor
Ain Shams University
Enrollment
80
Locations
1
Primary Endpoint
Postoperative opioid consumption
Status
Completed
Last Updated
last year

Overview

Brief Summary

In recent years , the popularity of ultrasound-guided fascial plane blocks has increased in achieving an effective postoperative analgesia and hence achieving enhanced recovery after surgery (ERAS) .

Mastering the use of ultrasound encourages anesthetists on the frequent use of regional anesthesia . Fascial plane blocks are increasingly becoming a part of multimodal analgesia as an alternative pain management strategy in cardiac surgery. Various regional techniques especially paravertebral plane blocks have been recently described to reduce the postoperative pain in cardiac surgery with enhanced recovery . Ultrasound-guided erector spinae plane block is a recently introduced technique for regional analgesia in thoracic neuropathic pain, rib fractures, and breast surgeries. This study aims to compare between the two techniques regarding their peri-operative analgesic effect and their impact on enhanced recovery after surgery.

Detailed Description

This study aims to compare between the effectiveness of Erector spinae plane block and thoracic paravertebral plane block in reducing the perioperative need of opioids in patients undergoing minimally invasive mitral valve replacement as part of ERAS.

Registry
clinicaltrials.gov
Start Date
March 24, 2022
End Date
March 30, 2025
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients with American Society of Anesthesiologists (ASA) score III.
  • Patients aged ≥ 18 years old.
  • Patients scheduled for minimally invasive mitral valve replacement through a right mini thoracotomy.

Exclusion Criteria

  • Patients refusing to be involved in this study.
  • Patients with ASA score \> III.
  • Patients aged \< 18 years.
  • Patients with local infection at the site of needle puncture.
  • Patients with known hypersensitivity to local anesthetic (LA).
  • Patients with hepatic or renal impairment.

Outcomes

Primary Outcomes

Postoperative opioid consumption

Time Frame: For 24 hours after extubation

morphine in milligram postoperatively

intraoperative opioid consumption

Time Frame: Through intraoperative period, average of 6 hours

Fentanyl in micrograms intraoperatively

Secondary Outcomes

  • Time for extubation(24 hours postoperative)
  • Time for ambulation(Through the stay of the patient in ICU postoperatively, average of 2 days.)
  • Postoperative respiratory depression(24 hours after extubation)
  • Length of ICU stay(Through patient's stay inicu till discharge to ward, average of 3 days)

Study Sites (1)

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