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临床试验/CTRI/2024/07/071423
CTRI/2024/07/071423尚未招募4 期

Combined Effectiveness Of Guggulutikthakam Kashaya pana and Sahacharadi taila Matravasti for Management of Pain in EndometriosisS.

Husni S1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2024年8月8日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
20
试验地点
1
主要终点
Change in dysmenorrhea dyspareunia, and chronic pelvic pain

研究概览

简要总结

Endometriosis is a chronic disease, characterized by implantation and growth of endometrial tissue outside the uterine cavity. Dysmenorrhea, dyspareunia and chronic pelvic pain are the most common symptoms. presence of endometrioma is often associated with endometriosis.Endometriosis is a tridosajanya vyadhi. Vitiated vata contributes to pain, pitta the inflammation and kapha the adhesions and endometrioma. Guggulutikthakam kashaya is kaphapitta samana and vatanulomana is widely used and found to help in relieving pain. Sahacharadi taila has an indication in yoniroga is widely used in gynaecological clinical practise for matravasti.

Subjects in the age group of 20-45 years with all inclusion and exclusion criteria are selected from the OPD. Guggulutikthakam kasaya 48ml given internally twice daily 1 hour before food  and Sahacharadi taila vastipaka given as matravasti at the dose of 60ml from the day after menstrual bleeding stops for 7 days. This combined treatment will be continued for 3 consecutive cycles. Change in dysmenorrhea, dyspareunia and chronic pelvic pain can be assessed on 0th,31st ,61st,91st day of study and 121st day for follow up, assessment done by visual decriptive scale and visual analogue scale. Also change in size of endometrioma is assessed on 0th day and 91st day by Ultrasoundsonography.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
20.00 Year(s) 至 45.00 Year(s)(—)
性别
Female

入选标准

  • Subjects, who are diagnosed with endometriosis and with any one or more of the symptoms like dysmenorrhea, dyspareunia and chronic pelvic pain.

排除标准

  • Endometriosis at remote site Uncontrolled systemic and chronic illness.
  • pregnancy and lactation.
  • irregular cycles.

结局指标

主要结局

Change in dysmenorrhea dyspareunia, and chronic pelvic pain

时间窗: 0th day,31st day,61st day,91st day.

次要结局

  • Change in size of endometrioma(0th day, 91st day.)

研究者

发起方
Husni S
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Husni S

Government Ayurveda Medical College and Hospital, Thiruvananthapuram

研究点 (1)

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