Androgen Replacement Therapy in Women With Hypopituitarism

Not Applicable

Completed

• Conditions: Hypopituitarism

• Registration Number: NCT00027430
• Lead Sponsor: Massachusetts General Hospital

Brief Summary

This is a study to determine whether testosterone replacement with TheraDerm can improve bone density, mood, sex drive, thinking, and distribution of body fat and muscle mass in women with hypopituitarism.

Detailed Description

Patients will be randomized into 2 groups to receive testosterone replacement therapy or placebo. Group 1 will receive 2 testosterone patches and estrogen pills for 12 months. Group 2 will receive 2 placebo patches and estrogen pills for 12 months. Changes in bone density, bone metabolism markers, body composition, libido, and quality of life will be compared in the women receiving testosterone replacement therapy with that of the women receiving placebo.

Completion date provided represents the completion date of the grant per OOPD records

Study Timeline

• Study Start: 2001-09
• Status Verified: 2001-11
• Study First Submitted: 2001-12-05
• Study First Submitted QC: 2001-12-06
• Study First Posted: 2001-12-07
• Study Completion: 2004-12
• Last Update Submitted: 2015-03-24
• Last Update Posted: 2015-03-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 50

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Trial Locations

Locations (1)

Massachusetts General Hospital; 🇺🇸 Boston, Massachusetts, United States