The Value of Near-infrared Spectroscopy and Blood Pressure Measurements in Estimating Future Fall Risk in Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 141
- 试验地点
- 1
- 主要终点
- Falls during follow-up
研究概览
简要总结
The investigators aim to study which measurements/definitions from continuous blood pressures measurements (using a Finometer) and from cerebral oxygenation measurements (using near-infrared spectroscopy (NIRS)) are associated with future fall incidents in older adults at risk of falls.
详细描述
Patients aged 65 years and over with a fall in the last 12 months are eligible for inclusion. After being informed about the study, all participants giving written informed consent will perform the active stand procedure (5min lying, 5 min standing). The hemodynamic measurements that will be performed during this procedure simultaneously consist of:
- Volume-clamp photoplethysmography on the finger in the digital artery (Finapres medical systems, Enschede, The Netherlands) for continuous blood pressure measurements.
- PortaLite MKII (Artinis medical systems, Elst, The Netherlands) for continuous cerebral oximetry (NIRS).
After completing the measurements, participants will receive a falls calendar and will be instructed to record falls, fall-related injuries, and fall-related healthcare use on a weekly basis for 12 months.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •65 years or older
- •History of a fall (in the past year)
- •Ability to perform supine-to-stand manoeuvres.
- •Ability to sign informed consent.
- •a Mini-Mental State Examination (MMSE) score of 21 points or higher or a Montreal Cognitive Assessment (MOCA) - Dutch score of 16 points or higher.
- •Sufficient command of the Dutch language
排除标准
- •Physically not able to perform sit-to-stand and supine-to-stand manoeuvres.
- •Estimated life expectancy of less than one year.
结局指标
主要结局
Falls during follow-up
时间窗: From enrollment to 12 months follow-up
Falls data prospectively collected using fall calenders.
次要结局
未报告次要终点
研究者
Prof. dr. Nathalie van der Velde
Prof.
University of Amsterdam