EUCTR2015-002366-23-AT
进行中（未招募）
1 期
Goal-directed heart rate control during emergence from anesthesia using esmolol to attenuate myocardial injury in patients undergoing non-cardiac surgery
Medical University of Vienna, Department of Anaesthesia, General Intensive Care and Pain Management0 个研究点目标入组 140 人2015年8月27日
概览
- 阶段
- 1 期
- 干预措施
- 未指定
- 疾病 / 适应症
- myocardial damage
- 发起方
- Medical University of Vienna, Department of Anaesthesia, General Intensive Care and Pain Management
- 入组人数
- 140
- 状态
- 进行中（未招募）
- 最后更新
- 7年前
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •\= 45 years
- •scheduled for elective major non\-cardiac surgery
- •general anesthesia (using general anesthetic drug(s) and opioids)
- •anticipated postoperative hospital stay for \> 2 days
- •no treatment with ß\-receptor blocking drugs for more than 30 days
- •increased cardiovascular risk because of history of coronary artery disease or a combination of \= 2 of the following risk factors: \= 70 years, congestive heart failure (NYHA \= II), chronic renal failure, smoking history, hypertension, diabetes, lipid\-lowering drug treatment or hypercholesterolemia, and obesity (BMI \> 35\).
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range 50
排除标准
- •patients who do not understand the informed consent
- •spinal or epidural anesthesia
- •history of ischemic cerebrovascular disease
- •severe asthma and COPD
- •preoperative heart rate \<61 beats per minute (bpm)
- •cardiac pacemaker
- •atrioventricular block type 2 and 3
- •sick sinus syndrome
- •sinoatrial block
- •cardiogenic shock
结局指标
主要结局
未指定
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