The Efficacy of Platelets Rich Plasma (PRP) for Ovarian Rejuvenation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Anti-Müllerian hormone (AMH) concentration
研究概览
简要总结
In recent years, an increased approach has appeared in the use of autologous blood products to assist tissue and organ healing. Application of platelet rich plasma (PRP) has emerged as a potential solution for infertile women with poor ovarian reserve in reproductive specialty.
详细描述
Quantitative and qualitative functional improvement of ovarian function has been reported in several studies after using autologous PRP in a reproductive field. Ovarian rejuvenation, stimulating the ovaries to produce new eggs after injecting PRP, can offer hope for renewed fertility to women with poor reserve volume, advanced maternal age, or either naturally occurring or premature menopause. But, these encouraging results should be supported by several new studies.
This study aimed to estimate the efficacy of trans-vaginal ovarian injection with PRP in rejuvenates ovaries in woman with poor ovarian reserve, and to assess any association of some women variables (age, menstrual status, parity, BMI) as predicting factors in success of ovarian injection with PRP.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 49 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Menopause or peri-menopause under the age of
- •Premature ovarian insufficiency which is ovarian failure before the age of
- •Woman with primary ovarian failure of any cause.
排除标准
- •A previous injection with any medication, plasma, or PRP
- •Invisible or difficult access ovaries.
- •Medical disease or unfit for anesthesia patient.
结局指标
主要结局
Anti-Müllerian hormone (AMH) concentration
时间窗: 4 weeks
Before after intervention measurement
Follicle-stimulating hormone (FSH) concentration
时间窗: 4 weeks
Before after intervention measurement
Antral follicles numbers
时间窗: 4 weeks
Before after intervention measurement
次要结局
未报告次要终点
研究者
Yousif Abdulraheem
Professor
Al-Kindy College of Medicine