Use of Platelet-Rich Plasma in Second-Degree Superficial Burns; Multicentric Prospective Randomized Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 62
- 试验地点
- 2
- 主要终点
- PRP use in second degree burn treatment
研究概览
简要总结
Platelet-rich plasma (PRP) obtained from the patient's blood has been used in many clinical and experimental studies, primarily wound healing, and successful results have been achieved.
PRP has been used in various studies in the treatment of burn wounds, and positive results have been obtained. However, investigators did not find any study or publication about the use of PRP in second-degree superficial burns in our screening.
Investigators planned a prospective randomized controlled and multicenter study to investigate the positive effects of PRP in the treatment of second-degree superficial burn.
详细描述
The study was planned to be performed between 01.03.2020 and 01.04.2020 in Health Sciences University Konya Training and Research Hospital Burn Unit and Health Sciences University Mogadishu-Somalia Recep Tayyip Erdogan Training and Research Hospital General Surgery Clinics.
Patients hospitalized with a second degree superficial burn and treated with PRP will be included in the study.
Primary purpose: To investigate the effectiveness of platelet-rich plasma in burn treatment Secondary purpose: None. Platelet-rich plasma has recently been used in medicine for the treatment of various diseases.
In our study, patients hospitalized in our clinic with the diagnosis of second-degree superficial burn were randomized and divided into two equal groups. It was planned to treat the first group with PRP, and the second group to be treated with a conventional method of dressing containing silver sulfadiazine cream.
Patients will be given clear and understandable information about the study. Patients who agree to participate in the study will receive a consent form explaining that they have participated in the study voluntarily.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 16 Years 至 90 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •having a second-degree superficial burn
- •To be over the age of 16.
排除标准
- •Patients under 16
- •Patients with a burn of more than 30% of the total body surface area.
- •Patients with additional trauma with a burn wound.
- •Diabetes mellitus, renal failure requiring dialysis and having decompensated heart disease
- •Being pregnant and breastfeeding.
- •The patient does not want to participate in the study.
结局指标
主要结局
PRP use in second degree burn treatment
时间窗: 01.03.2020-30.04.2020
In the study, the effectiveness of burn treatment in both groups will be determined by recording the day of epithelialization.
次要结局
未报告次要终点
研究者
Alpaslan Şahin
Principal Investigator
Konya Meram State Hospital