Mucosal Impedance and Eosinophilic Esophagitis

Not Applicable

Completed

• Conditions: Eosinophilic Esophagitis

• Registration Number: NCT01953575
• Lead Sponsor: Mayo Clinic

Brief Summary

Do patients with eosinophilic esophagitis have baseline increased esophageal mucosal impedance?

And will treatment that reverses esophageal eosinophilia in patients, correct abnormalities in mucosal impedance?

Detailed Description

Not available

Study Timeline

• Study Start: 2013-09
• Study First Submitted: 2013-09-26
• Study First Submitted QC: 2013-09-26
• Study First Posted: 2013-10-01
• Primary Completion: 2019-06-10
• Study Completion: 2019-06-10
• Status Verified: 2020-04
• Results First Submitted: 2020-04-01
• Results First Submitted QC: 2020-04-01
• Last Update Submitted: 2020-04-01
• Results First Posted: 2020-04-15
• Last Update Posted: 2020-04-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Esophageal Mucosal Impedance (MI)	baseline to one year	An endoscopically placed probe measured electrical impedance of the esophageal lining by direct mucosal contact. Impedance measurements of the esophageal mucosa were expressed in ohms as the ratio of voltage to current Impedance measurements were obtained at 2, 5, 10, and 15 cm above the gastroesophageal junction.

Trial Locations

Locations (1)

Mayo Clinic in Rochester; 🇺🇸 Rochester, Minnesota, United States