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Out Patient Surgery for Total Knee and Hip Replacement and Unicompartmental Knee Replacement - a Feasibility Study

Completed
Conditions
Osteoarthritis
Interventions
Other: Does fulfil of discharge criteria on the day of the surgery
Other: Does not fulfil of discharge criteria on the day of the surgery
Registration Number
NCT02544620
Lead Sponsor
Kirill Gromov
Brief Summary

The purpose of this study is to evaluate feasibly of outpatient Total Knee Replacement, Total Hip Replacement and Unicompartmental Knee Replacement in a modern fast-track setup. The design is as an observational prospective study, evaluating patients that fulfil discharge criteria on the day of the surgery. The investigators will further evaluate safety aspects, such a early morbidity and mortality, as well as patient satisfaction.

Detailed Description

Fast-track total hip arthroplasty (THA), total knee arthroplasty (TKA) and Unicompartmental Knee arthroplasty (UKA) with length of stay (LOS) of 1-3 is a well established concept for treating hip and knee osteoarthritis, resulting in short reconvalescence, high patient satisfaction, and an excellent safety profile (lower or similar mortality / morbidity compared to conventional pathways with longer LOS). LOS have been significantly reduced during the past decade, and several centers have published even shorter hospitals stays: \<24 hours, with patients staying the night at the hospital but also outpatient surgery, with patients being discharged on the day of surgery.

However, these proposed pathways with extremely short LOS, are performed on very selected patients, with few details on patient satisfaction, outcome and most important patient safety. Therefore, it is not possible to draw conclusions on feasibility of outpatient THA, TKA and UKA surgery in a general and unselected population. Further on, there is a need for investigation of safety aspects of outpatient surgery in respect to mortality, morbidity, patient satisfaction and patient reported outcomes. As some, most likely healthy and younger, patients might benefit from outpatient surgery - eg discharge on the day of surgery, while others might not; the first step is to identify the patients that are suitable for outpatient THA and TKA surgery and investigate the safety aspects in respect to mortality, morbidity, patient satisfaction and patient reported outcomes.

Aim:

The aim of this study is to investigate "feasibility" and "safety" of outpatient THA, TKA and UKA surgery, respectively as follows:

Feasibility

* Proportion of patients, that can be included in the study according to inclusion criteria stated below, and be evaluated for potential same-day discharge (I) (I = included)

* Proportion of included patients (I), that are discharged on the day of surgery (U) and those who are not discharged and stay for \>1 day (B)

* Identify reasons for patients not being able to be discharged on the day of surgery (B)

Safety

* risk for complications (morbidity) in group (U) compared to group (B) (are there complications that potentially could have been avoided is the patient was not discharged)

* readmissions in group (U ) compared to group (B) within 90 days

* mortality in group (U ) compared to group (B) within 90 days

* patient satisfaction in group (U ) compared to group (B)

* Patient reported outcome (Oxford knee score + range of motion for TKA and UKA group, and Oxford hip score for THA group) in group (U) compared to group (B)

* contacts to primary sector in group (U ) compared to group (B) within 7 days.

* use of rescue morphine (pain journal) for 7 days post op in group (U ) compared to group (B)

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1000
Inclusion Criteria
  • Unselected primary THA/TKA
  • ASA score I/II
  • Can be operated as #1 or #2
  • No sleep apnea treated with CPAP
Exclusion Criteria
  • Selected primary THA/TKA
  • ASA score > 2
  • Cannot be operated as #1 or #2
  • Sleep apnea treated with CPAP

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Total Hip arthroplastyDoes fulfil of discharge criteria on the day of the surgery* Unselected primary THA * American Society of Anesthesiologists (ASA) score I/II * Can be operated as #1 or #2 * No sleep apnea treated with Continuous positive airway pressure (CPAP)
Total Knee arthroplastyDoes fulfil of discharge criteria on the day of the surgery* Unselected primary TKA * American Society of Anesthesiologists (ASA) score I/II * Can be operated as #1 or #2 * No sleep apnea treated with Continuous positive airway pressure (CPAP)
Total Knee arthroplastyDoes not fulfil of discharge criteria on the day of the surgery* Unselected primary TKA * American Society of Anesthesiologists (ASA) score I/II * Can be operated as #1 or #2 * No sleep apnea treated with Continuous positive airway pressure (CPAP)
Total Hip arthroplastyDoes not fulfil of discharge criteria on the day of the surgery* Unselected primary THA * American Society of Anesthesiologists (ASA) score I/II * Can be operated as #1 or #2 * No sleep apnea treated with Continuous positive airway pressure (CPAP)
unicompartmental knee arthroplastyDoes fulfil of discharge criteria on the day of the surgery* Unselected primary UKA * American Society of Anesthesiologists (ASA) score I/II * Can be operated as #1 or #2 * No sleep apnea treated with Continuous positive airway pressure (CPAP)
unicompartmental knee arthroplastyDoes not fulfil of discharge criteria on the day of the surgery* Unselected primary UKA * American Society of Anesthesiologists (ASA) score I/II * Can be operated as #1 or #2 * No sleep apnea treated with Continuous positive airway pressure (CPAP)
Primary Outcome Measures
NameTimeMethod
Fulfilment of same day discharge criteria12 hours

On the days of surgery following discharge criteria are continuously evaluated:

* \< 500 ml intraoperative blood loss

* Back in patient ward \<15.00

* Received instruction from physiotherapist and is safely mobilized

* No clinical symptoms of anemia

* Pain \<3 while resting, \<5 during exercise.

* Spontaneous urination

* Post op x-ray is performed and approved

* Relatives or friends with patient for \>24 hours

* Motivated and accepts same day discharge

* Standard discharge criteria fulfilled

* Can be discharged before 20.00

If all of the above criteria are fulfilled, the patient can be discharged

Secondary Outcome Measures
NameTimeMethod
Patient reported satisfaction3 months

OKS (Oxford Knee score) and ROM (Range og motion) for TKA and UKA, OHS for THA

Use of rescue morphine7 days
Readmissions3 months

Trial Locations

Locations (1)

Hvidovre Hospital

🇩🇰

Hvidovre, Denmark

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