A non-inferiority randomized controlled trial to evaluate the efficacy and safety of automated delivery of three anesthetics using a robotic anesthesia system for total intravenous anesthesia with propofol, remifentanil, and rocuronium - A non-inferiority randomized controlled trial of automated delivery of three intravenous anesthetics using a robotic anesthesia system for total intravenous anesthesia

We obtained useful criteria to assess the appropriate level of analgesia that satisfies the anesthesiologist by examining in detail the information obtained from the interval when the anesthesiologists judged that the patient was in a stable analgesic state during observation period. As the non-inferiority of AC group was indicated with the revised criteria obtained in this study, our criteria will be appropriate for evaluating the effectiveness of automated-control system in future studies.