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Clinical Trials/CTRI/2025/07/091512
CTRI/2025/07/091512
Not yet recruiting
Phase 2/3

Efficacy Of Lesser Known Homoeopathic Medicines In Treatment Of Haemorrhoids – A Clinical Study

S S Agrawal Homoeopathic Medical College and General Hospital1 site in 1 country80 target enrollmentStarted: August 2, 2025Last updated:

Overview

Phase
Phase 2/3
Status
Not yet recruiting
Sponsor
S S Agrawal Homoeopathic Medical College and General Hospital
Enrollment
80
Locations
1
Primary Endpoint
To assess the efficacy of lesser known homoeopathic medicines in treatment of haemorrhoids.

Overview

Brief Summary

This clinical study titled “Efficacy of Lesser Known Homoeopathic Medicines in the Treatment of Haemorrhoids – A Clinical Study” aims to evaluate the effectiveness of lesser-known homoeopathic medicines—Aegle folia, Gratiola officinalis, Mancinella, and Strontium carbonicum—in the treatment of haemorrhoids. It is a prospective, interventional, open-label, single-arm clinical trial, where all participants will receive one of the selected homoeopathic remedies based on individualization and symptom totality. The study will be conducted on 80 patients, aged 15 to 65 years, of either gender, who are clinically diagnosed with internal or external haemorrhoids and are willing to undergo homoeopathic treatment. Patients requiring emergency surgery, pregnant/lactating women, or those under malignant disease condition  will be excluded. The primary outcome will be measured using the Haemorrhoid Symptom Severity Scale (HSSS) before and after treatment. Secondary objectives include assessing incidence by age, sex, occupation, identifying the most effective medicine among the selected ones. The study will span nine months, including recruitment, treatment, and follow-up phases. The site of study will be S S AGRAWAL  Homoeopathic Medical College and General Hospital OPD at Navsari. The trial has received ethical approval from the Institutional Ethics Committee. The study is led by Dr. Disha Patel , a Postgraduate Scholar from the Department of Homoeopathic Materia Medica.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
None

Eligibility Criteria

Ages
15.00 Year(s) to 65.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • 1.Both sexes and all types of socio economical status.
  • 2.Diagnostic criteria are mainly based on the clinical presentation.
  • 3.Diagnosed cases of Haemorrhoids, taking treatment from other system of medicine and in homoeopathy treatment only those cases will be included where the treatment given with the four homoeopathic medicine being studied, feeling no relief or recurrence or under control but seeking Homoeopathic treatment.

Exclusion Criteria

  • 1.Patients of age group below 15 years and above 65 years.
  • 2.Pregnant women 3.Cases with complication like heavy bleeding , fissure in ano , fistula in ano , malignancy , crohn’s disease , ulcerative colitis and other diseases having rectal complaints secondary phenomena are excluded.
  • 4.Patients having other severe systemic disorders .
  • 5.The cases, who do not continue with treatment up to six visits, were dropped out of the study.

Outcomes

Primary Outcomes

To assess the efficacy of lesser known homoeopathic medicines in treatment of haemorrhoids.

Time Frame: 9 Months

Secondary Outcomes

  • To compare the symptomatic relief before and after treatment with the help of Haemorrhoid Symptom severity scale.(9 Months)

Investigators

Sponsor
S S Agrawal Homoeopathic Medical College and General Hospital
Sponsor Class
Private medical college
Responsible Party
Principal Investigator
Principal Investigator

Disha Kumari Ratilal Patel

S. S. Agrawal Homoeopathic Medical College And General Hospital , Navsari

Study Sites (1)

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